ENHANCED RECOVERY AFTER SURGERY (ERAS) IN EMERGENCY COLORECTAL SURGERY

  • Marius Lazar University of Medicine and Pharmacy of Craiova, Surgery Department
  • Marius Bica University of Medicine and Pharmacy of Craiova, Surgery Department
  • Valeriu Surlin University of Medicine and Pharmacy of Craiova, Surgery Department
Keywords: emergency, colorectal surgery, ERAS, compliance

Abstract

Introduction: Enhanced recovery after surgery (ERAS) programs for elective colorectal surgery have been shown to decrease postoperative complication, shorten hospital stay, facilitate patient recovery, and lower healthcare cost. The question if ERAS programs applied in emergency colorectal surgery can have the same benefits still awaits a definitive answer. Material and method: We performed a prospective analysis of patients with complicated colorectal cancer admitted to our department between 2020 and 2023. ERAS protocol measures were applied to all patients. We studied the compliance with each item of the protocol. We selected the patients with a minimum of 12 ERAS measures applied. We compared them with a similar group selected from previous addmitions through a matching case process. We followed: GI recovery time, hospital stay, postoperative complications, overall morbidity, and mortality rates. Results: The rates of compliance were significantly lower for preoperative and postoperative measures in emergency when compared to elective surgery but similar for intraoperative measures. 63 patients that had a minimum of 12 ERAS measures applied. We compared them with the matched cases group. There was a significantly lower GI recovery time for patients in the ERAS group compared to non-ERAS patients. (mean values 54.4 hours vs. 75.2 hours). Also, the hospital stay was significantly lower for the ERAS Group (mean values 7.4 days vs. 10.8 days). Postoperative morbidity and mortality were similar in the two Groups. Conclusion: The ERAS program is associated with a faster GI recovery time and shorter length of hospital stay – without increased rates of morbidity and mortality after emergency colorectal surgery. Compliance with ERAS program in emergency surgery appears to be lower than in elective operations.

References

1. Greer NL, Gunnar WP, Dahm P, Lee AE, MacDonald R, Shaukat A, Sultan S, Wilt TJ. Enhanced Recovery Protocols for Adults Undergoing Colorectal Surgery: A Systematic Review and Meta-analysis. Dis Colon Rectum. 2018; 61:1108–1118.
2. Lemanu DP, Singh PP, Stowers MD, Hill AG. A systematic review to assess cost effectiveness of enhanced recovery after surgery programmes in colorectal surgery. Colorectal Dis. 2014; 16:338–346.
3. Gustafsson UO, Oppelstrup H, Thorell A, Nygren J, Ljungqvist O. Adherence to the ERAS protocol is Associated with 5-Year Survival After Colorectal Cancer Surgery: A Retrospective Cohort Study. World J Surg. 2016; 40:1741–1747.
4. Carmichael JC, Keller DS, Baldini G, Bordeianou L, Weiss E, Lee L, Boutros M, McClane J, Feldman LS, Steele SR. Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery From the American Society of Colon and Rectal Surgeons and Society of American Gastrointestinal and Endoscopic Surgeons. Dis Colon Rectum. 2017;60:761–784.
5. Gunnarsson H, Jennische K, Forssell S, et al. Heterogeneity of colon cancer patients reported as emergencies. World J Surg. 2014;38(7):1819–1826.
6. Renzi C, Lyratzopoulos G, Card T, Chu TP, Macleod U, Rachet B. Do colorectal cancer patients diagnosed as an emergency differ from non-emergency patients in their consultation patterns and symptoms? A longitudinal data-linkage study in England. Br J Cancer. 2016;115(7):866–875.
7. Bayar B, Yılmaz KB, Akıncı M, Şahin A, Kulaçoğlu H. An evaluation of treatment results of emergency versus elective surgery in colorectal cancer patients. Ulus Cerrahi Derg. 2015;32:11–17
8. Ho KS, Quah HM, Lim JF, Tang CL, Eu KW. Endoscopic stenting and elective surgery versus emergency surgery for left-sided malignant colonic obstruction: a prospective randomized trial. Int J Colorectal Dis. 2012;27:355–362.
9. Gustafsson, U.O., Scott, M.J., Hubner, M. et al. Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018. World J Surg 43, 659–695 (2019). https://doi.org/10.1007/s00268-018-4844-y
10. Viñas, X., Macarulla, E., Brugiotti, C. et al. Feasibility and effects of enhanced recovery vs. conventional care after emergency colon surgery for patients with left colon perforation. Sci Rep 10, 7346 (2020). https://doi.org/10.1038/s41598-020-64242-7
11. Lohsiriwat V. Enhanced recovery after surgery vs conventional care in emergency colorectal surgery. World J Gastroenterol. 2014;20:13950–13955.
12. Wisely JC, Barclay KL. Effects of an Enhanced Recovery After Surgery programme on emergency surgical patients. ANZ J Surg. 2016;86:883–888.
13. Shida D, Tagawa K, Inada K, Nasu K, Seyama Y, Maeshiro T, Miyamoto S, Inoue S, Umekita N. Modified enhanced recovery after surgery (ERAS) protocols for patients with obstructive colorectal cancer. BMC Surg. 2017;17:18.
14. Shang Y, Guo C, Zhang D. Modified enhanced recovery after surgery protocols are beneficial for postoperative recovery for patients undergoing emergency surgery for obstructive colorectal cancer: A propensity score matching analysis. Medicine(Baltimore) 2018;97: e12348.
15. Lohsiriwat V, Jitmungngan R, Chadbunchachai W, Ungprasert P. Enhanced recovery after surgery in emergency resection for obstructive colorectal cancer: a systematic review and meta-analysis. Int J Colorectal Dis. 2020 Aug;35(8):1453-1461. doi: 10.1007/s00384-020-03652-5. Epub 2020 Jun 22. PMID: 32572602.
16. Verheijen PM, Vd Ven AW, Davids PH, Vd Wall BJ, Pronk A. Feasibility of enhanced recovery programme in various patient groups. Int J Colorectal Dis. 2012;27:507–511
17. Roulin D, Blanc C, Muradbegovic M, Hahnloser D, Demartines N, Hübner M. Enhanced recovery pathway for urgent colectomy. World J Surg. 2014;38:2153–2159.
18. Gonenc M, Dural AC, Celik F, Akarsu C, Kocatas A, Kalayci MU, Dogan Y, Alis H. Enhanced postoperative recovery pathways in emergency surgery: a randomised controlled clinical trial. Am J Surg. 2014;207:807–814.
19. Lohsiriwat V. Enhanced recovery after surgery for emergency colorectal surgery: Are there any differences between intraabdominal infection and other indications? J Visc Surg. 2019
Published
2024-06-27