• Denisa-Andreea Dorneanu “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania
  • Mihaela Plotogea “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania
  • Claudia Mehedintu 1“Nicolae Malaxa” Clinical Hospital, Bucharest, Romania; 2“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
  • Francesca Frincu “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
  • Andreea Carp-Veliscu “Carol Davila” University of Medicine and Pharmacy", Bucharest, Romania
  • Mihai Dumitrascu “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
  • Aida Petca “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
  • Monica Mihaela Cirstoiu “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
  • Antoine Edu “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
  • Radu Mateescu “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Keywords: extrauterine pregnancy, ectopic pregnancy, pregnancy with unspecified location, cervical ectopic pregnancy, post-caesarean scar ectopic pregnancy, abdominal ectopic pregnancy, methotrexate, laparoscopy.


Any pregnancy outside the endometrial cavity is defined as extrauterine pregnancy (EUP) or ectopic pregnancy (EP). It is an acute and important complication of the first trimester of pregnancy that can be associated with a high risk of morbidity and mortality for the patient. Most extrauterine pregnancies (EUP) (more than 95%) are in the salpinx. In the fallopian tube, the locations are 13% isthmic, 75% ampullary, and 12% fimbrial. The prevalence of ectopic pregnancy ranges from 6-16% of all pregnancies, with an increasing incidence in recent years due to assisted reproductive technologies. Half of the women of reproductive age diagnosed with ectopic pregnancy have no known risk factors.


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